Logo des HTGF

Portfolio Jobs

Browse through our portfolio jobs and select a suitable opportunity.

Our HTGF Portfolio of startups offers excellent opportunities and is always hiring talented people.

0
COMPANIES
0
JOBS

Senior Scientist - Cell Line & USP Development (m/f/d)

Tubulis Technologies

Tubulis Technologies

Munich, Germany · Germany · Bavaria, Germany
Posted on Feb 28, 2026
Be part of our team
The Position within Tubulis’ Chemistry Manufacturing & Control team is responsible for the external development of high-performing production cell lines as well as developing robust and efficient cell culture processes. Additionally, this role supports GMP technology transfer of upstream processes to GMP manufacturing in our Contract Manufacturing network.
Your mission
  • Oversee the generation and characterization of stable production cell lines for recombinant antibody modalities
  • Manage the cell banking of Research, Master, and Working Cell banks across Tubulis’ portfolio
  • Act as the subject matter expert during the design, development and optimization of scalable upstream processes
  • Support scale-up and technology transfer activities to pilot and GMP manufacturing sites
  • Author and review development reports, risk assessments, batch records and relevant CMC sections for regulatory dossiers, etc.
  • Close collaboration with Quality Assurance, Regulatory Affairs and external partners
Your profile
Must-Have Qualifications:
  • A university degree in biotechnology, biochemistry, or related subjects (B.Sc. or M.Sc.)
  • Min. 5 years combined working experience (M.Sc.)/min 8 years combined working experience (B.Sc.) in cell line development and Upstream Processing of recombinant proteins
  • Strong expertise with CHO cell lines, transfection, single cell cloning, and high throughput clone screening technologies.
  • Strong understanding of global CMC regulatory requirements, including ICH guidelines and expectations from EMA, FDA, and/or other health authorities.
  • Know-how in GxP to efficiently communicate between development, quality, and regulatory functions
  • Good proficiency in spoken and written English is a must
  • Experience in downstream processing of therapeutic proteins is a plus

Nice-to-Have Qualifications:
  • Downstream Development & Manufacturing
Why us?
At Tubulis, curiosity and innovation drive us to transform cancer treatment. We are a fast-growing biotech where science meets passion—and where you have the chance to grow with us.
  • Impact that matters: Contribute to breakthrough therapies.
  • Global mindset: Work in an international, diverse team.
  • Grow & thrive: Develop your career in a supportive, fast-moving environment.
  • Innovation every day: Push boundaries with cutting-edge science.
At Tubulis, your ideas matter, your growth matters—and together, we make a difference.
About us
Tubulis is a clinical stage biotech company that generates uniquely matched antibody-drug conjugates (ADCs) with superior biophysical properties that have demonstrated durable on-tumor delivery and long-lasting anti-tumor activity in preclinical models. We recently closed on a Series C fundraising round totaling €344M (US $401M).

The development of novel, effective and safe therapies for the treatment of cancer is one of the main challenges for modern medicine. We want to drive this process forward. The main goal of Tubulis is to become a leading company in the field of targeted therapeutics and ADCs. With a strong team, our own technologies and innovative therapeutic concepts, we are ushering in a new era in the ongoing fight against cancer and share the vision of helping patients world-wide. Be part of a multidisciplinary and focused team, that works towards getting novel promising ADCs to patients with solid and hematological cancers.