Pantherna Therapeutics is a privately held mRNA therapeutics company developing novel first-in-class therapies for indications with high unmet medical need. Pantherna’s development programs are based on two innovative and proprietary PTX platform technologies, offering robust mRNA expression constructs (PTX-mRNA) and lipid nanoparticle (LNP) delivery vehicles (PTX-LNP) for localized expression of therapeutic proteins. PAN004 is Pantherna’s first development candidate derived from this platform, representing a defined mRNA-LNP formulation for selective mRNA delivery and expression of a Tie2-agonist in the vascular endothelium of the lung. Pantherna strives for expanding its pipeline with various novel mRNA-LNP candidates enabling the therapeutic use of mRNA beyond the vascular endothelium in distinct tissues such as skeletal muscle or immune cells.

Hennigsdorf, Germany

Pantherna Therapeutics GMBH

The seed investor High-Tech Gründerfonds (HTGF) finances tech start-ups with growth potential and has supported more than 700 start-ups since 2005. With the launch of its fourth fund, HTGF now has about 1.4 billion euros under management. Its team of experienced investment managers and start-up experts support young companies with expertise, entrepreneurial spirit and passion. HTGF’s focus is on high-tech start-ups in the fields of digital tech, industrial tech, life sciences, chemistry and related business areas. To date, external investors have injected about 5 billion euros of capital into the HTGF portfolio via more than 2,000 follow-on financing rounds. In addition, HTGF has already successfully sold shares in more than 170 companies. Fund investors in this public-private partnership include the German Federal Ministry for Economic Affairs and Climate Action, KfW Capital and 45 companies from a wide range of industries. Fund investors in this public-private partnership include the German Federal Ministry for Economic Affairs and Climate Action, KfW Capital and 45 companies from a wide range of industries.

High-Tech Gründerfonds Management GmbH

HTGF 

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As our companies grow, they look to us to help them find the best talent.
Signal that you'd be interested in working with a HTGF company to help us put the right opportunities at great companies on your radar. The choice to pursue a new career move is then up to you.

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Browse through our portfolio jobs and select a suitable opportunity.Our HTGF Portfolio of startups offers excellent opportunities and is always hiring talented people.

Browse through our portfolio jobs and select a suitable opportunity.
Our HTGF Portfolio of startups offers excellent opportunities and is always hiring talented people.